Pathway Details

Recommended name

Glycine, Serine and Threonine metabolism

Alternative names

Reactions

ATP + L-Serine + tRNA(Ser) <-> Diphosphate + AMP + L-Seryl-tRNA(Ser)

Glycerate 3-phosphate + H2O <-> Phosphate + D-Glycerate

ATP + L-Homoserine <-> ADP + O-Phospho-L-homoserine

H+ + NADPH + Methylglyoxal <-> NADP+ + Hydroxyacetone

NADP+ + Dihydrolipoylprotein <-> H+ + NADPH + Lipoylprotein

H2O + O-Phospho-L-homoserine <-> Phosphate + L-Threonine

NAD+ + L-Threonine <-> NADH + H+ + 2-Amino-acetoacetate

CO2 + Aminoacetone <-> L-2-Amino-3-oxobutanoate

H2O + O2 + Betaine aldehyde <-> H2O2 + Betaine

2-Phosphoglycerate <-> Glycerate 3-phosphate

NAD+ + H2O + Betaine aldehyde <-> NADH + H+ + Betaine

L-Serine + (3-Indolyl)-glycerol phosphate <-> D-Glyceraldehyde 3-phosphate + H2O + L-Tryptophan

L-Serine <-> D-Serine

L-Serine + CDP-1,2-diacylglycerol <-> CMP + Phosphatidylserine

ATP + L-Threonine + tRNA(Thr) <-> Diphosphate + AMP + L-Threonyl-tRNA(Thr)

H2O + Glycine + 5,10-Methylenetetrahydrofolate <-> L-Serine + 5,6,7,8-Tetrahydrofolate

S-Adenosyl-L-methionine + Phosphatidyl-N-dimethylethanolamine <-> S-Adenosyl-L-homocysteine + Phosphatidylcholine

5,6,7,8-Tetrahydrofolate + S-Aminomethyldihydrolipoylprotein <-> NH3 + 5,10-Methylenetetrahydrofolate + Dihydrolipoylprotein

H2O + O-Phospho-L-serine <-> Phosphate + Serine

ATP + Choline <-> ADP + Choline phosphate

NAD+ + (R)-1-Aminopropan-2-ol <-> NADH + H+ + Aminoacetone

H2O + Sarcosine + Acceptor <-> Glycine + Formaldehyde + Reduced acceptor

L-Serine + Sulfide <-> H2O + L-Cysteine

Glycine + 2-Oxoglutarate <-> L-Glutamate + Glyoxylate

2-Oxoglutarate + O-Phospho-L-serine <-> L-Glutamate + 3-Phosphohydroxypyruvate

O2 + 2 Choline <-> 2 H2O + 2 Betaine aldehyde

S-Adenosyl-L-methionine + Phosphatidylethanolamine <-> S-Adenosyl-L-homocysteine + Phosphatidyl-N-methylethanolamine

H2O + Phosphatidylcholine <-> Choline phosphate + 1,2-Diacyl-sn-glycerol

Pyruvate + L-Serine <-> L-Alanine + 3-Hydroxypyruvate

H2O + Phosphatidylethanolamine <-> Ethanolamine phosphate + 1,2-Diacyl-sn-glycerol

L-Serine + 5,6,7,8-Tetrahydromethanopterin <-> H2O + Glycine + 5,10-Methylenetetrahydromethanopterin

Phosphatidylserine <-> CO2 + Phosphatidylethanolamine

NADP+ + L-Homoserine <-> H+ + NADPH + L-Aspartate 4-semialdehyde

H2O + O2 + Sarcosine <-> Glycine + H2O2 + Formaldehyde

H2O + Glycine + O2 <-> NH3 + Glyoxylate + H2O2

ATP + L-Aspartate <-> ADP + 4-Phospho-L-aspartate

L-allo-Threonine <-> Glycine + Acetaldehyde

H2O + O2 + N,N-Dimethylglycine <-> H2O2 + Formaldehyde + Sarcosine

H2O + 3-Phospho-D-glycerate <-> Phosphate + D-Glycerate

H2O + O2 + Aminoacetone <-> NH3 + H2O2 + Methylglyoxal

Glycine + Succinyl-CoA <-> Coenzyme A + 2-Amino-3-oxoadipate

H2O + Glycine + 2 Ferricytochrome c <-> NH3 + Glyoxylate + 2 Ferrocytochrome c

3-Phospho-D-glycerate <-> 2-Phospho-D-glycerate

Glycine + Acetyl-CoA <-> Coenzyme A + 2-Amino-acetoacetate

Choline + Acceptor <-> Reduced acceptor + Betaine aldehyde

Glycine + Lipoylprotein <-> CO2 + S-Aminomethyldihydrolipoylprotein

O2 + Choline <-> H2O2 + Betaine aldehyde

H2O + FAD + Betaine aldehyde <-> FADH2 + Betaine

2 H+ + O2 + Choline + 2 Reduced ferredoxin <-> 2 H2O + 2 Oxidized ferredoxin + Betaine aldehyde

H2O + O-Phospho-L-serine <-> Phosphate + L-Serine

D-Serine <-> Pyruvate + NH3

Phosphate + NADP+ + L-Aspartate 4-semialdehyde <-> H+ + NADPH + 4-Phospho-L-aspartate

ATP + D-Glycerate <-> 2-Phospho-D-glycerate + ADP

Glycine + S-Adenosyl-L-methionine <-> S-Adenosyl-L-homocysteine + Sarcosine

Glycine + Succinyl-CoA <-> Coenzyme A + CO2 + 5-Aminolevulinate

L-Threonine + NADP+ <-> H+ + NADPH + L-2-Amino-3-oxobutanoate

NADP+ + D-Glycerate <-> H+ + NADPH + 3-Hydroxypyruvate

ATP + Glycine + tRNA(Gly) <-> Diphosphate + AMP + Glycyl-tRNA(Gly)

Glycine + L-Arginine <-> L-Ornithine + Guanidinoacetate

L-Alanine + Glyoxylate <-> Pyruvate + Glycine

Acetyl-CoA + L-2,4-Diaminobutanoate <-> Coenzyme A + N-gamma-Acetyldiaminobutyrate

D-Serine + Arginine <-> Ornithine + Lombricine

H2O + NADP+ + Betaine aldehyde <-> H+ + NADPH + Betaine

NAD+ + 3-Phospho-D-glycerate <-> NADH + H+ + 3-Phosphohydroxypyruvate

S-Adenosyl-L-methionine + N,N-Dimethylglycine <-> S-Adenosyl-L-homocysteine + Betaine

2-Amino-3-oxoadipate <-> CO2 + 5-Aminolevulinate

ATP + D-Glycerate <-> ADP + 3-Phospho-D-glycerate

Glycerate 3-phosphate + NAD+ <-> NADH + H+ + 3-Phosphohydroxypyruvate

NADH + H+ + 3-Hydroxypyruvate <-> NAD+ + Glycerate

S-Adenosyl-L-methionine + Guanidinoacetate <-> S-Adenosyl-L-homocysteine + Creatine

L-Serine + (3-Indolyl)-glycerol phosphate <-> H2O + L-Tryptophan + Glyceraldehyde 3-phosphate

N-gamma-Acetyldiaminobutyrate <-> H2O + Ectoine

ATP + Lombricine <-> ADP + N-Phospholombricine

L-Homocysteine + Betaine <-> L-Methionine + N,N-Dimethylglycine

Glycine + Acetyl-CoA <-> Coenzyme A + L-2-Amino-3-oxobutanoate

NAD+ + L-Homoserine <-> NADH + H+ + L-Aspartate 4-semialdehyde

NAD+ + D-Glycerate <-> NADH + H+ + 3-Hydroxypyruvate

L-Serine + Glyoxylate <-> Glycine + 3-Hydroxypyruvate

NAD+ + L-Threonine <-> NADH + H+ + L-2-Amino-3-oxobutanoate

L-2,4-Diaminobutanoate <-> CO2 + 1,3-Diaminopropane

L-Glutamate + L-Aspartate 4-semialdehyde <-> 2-Oxoglutarate + L-2,4-Diaminobutanoate

H2O + L-Cystathionine <-> L-Cysteine + NH3 + 2-Oxobutyrate

H2O + Acceptor + N,N-Dimethylglycine <-> Formaldehyde + Sarcosine + Reduced acceptor

Glycerate 3-phosphate + H2O <-> Phosphate + Glycerate

NAD+ + Dihydrolipoylprotein <-> NADH + H+ + Lipoylprotein

L-Serine + L-Homocysteine <-> H2O + L-Cystathionine

L-Threonine <-> Glycine + Acetaldehyde

L-Threonine <-> NH3 + 2-Oxobutyrate

S-Adenosyl-L-methionine + Phosphatidyl-N-methylethanolamine <-> S-Adenosyl-L-homocysteine + Phosphatidyl-N-dimethylethanolamine

L-Serine <-> Pyruvate + NH3

Classification

Amino Acid Metabolism