Enzyme Details

EC Classification

1.1.1.169

Enzyme name
(recommended)

2-dehydropantoate 2-reductase

Alternative names

(R)-pantoate:NADP+ 2-oxidoreductase
2-oxopantoate reductase
2-ketopantoate reductase
2-ketopantoic acid reductase
ketopantoate reductase
ketopantoic acid reductase

Classification

Oxidoreductases

Acting on the CH-OH group of donors

With NAD(+) or NADP(+) as acceptor

Catalyses reactions

NADP+ + (R)-Pantoate <-> H+ + NADPH + 2-Dehydropantoate

2-Dehydropantoate + 3'-NADPH <-> (R)-Pantoate + 3'-NADP+

2-Dehydropantoate + 3-APADPH <-> (R)-Pantoate + 3-APADP+

2-Dehydropantoate + NHDPH <-> (R)-Pantoate + NHDP+

2-Dehydropantoate + alpha-NADPH <-> (R)-Pantoate + alpha-NADP+

2-Dehydropantoate + tNADPH <-> (R)-Pantoate + tNADP+

H+ + NADPH + 3-Methyl-2-oxopentanoate <-> NADP+ + 2-Hydroxy-3-methyl-n-valerate

H+ + NADPH + alpha-Ketovaline <-> NADP+ + Hydroxyisovalerate

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 1.1.1.169