Enzyme Details

 EC Classification 1.1.1.188
 Enzyme name
(recommended)		 prostaglandin-F synthase
 Alternative names (5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate:NADP+ 11-oxidoreductase
prostaglandin-D2 11-reductase
reductase, 15-hydroxy-11-oxoprostaglandin
PGD2 11-ketoreductase
PGF2alpha synthetase
prostaglandin 11-ketoreductase
prostaglandin D2-ketoreductase
prostaglandin F synthase
prostaglandin F synthetase
synthetase, prostaglandin F2alpha
PGF synthetase
NADPH-dependent prostaglandin D2 11-keto reductase
prostaglandin 11-keto reductase
 Classification
Oxidoreductases
Acting on the CH-OH group of donors
With NAD(+) or NADP(+) as acceptor
 Catalyses reactions
NADP+ + Xylitol <-> H+ + NADPH + D-Xylose
NADP+ + Prostaglandin F2alpha <-> H+ + NADPH + Prostaglandin D2
11-epi-Prostaglandin F2alpha <-> 2 H+ + Prostaglandin D2
H+ + NADPH + Butanal <-> NADP+ + 1-Butanol
H+ + NADPH + Glyceraldehyde <-> NADP+ + Glycerol
H+ + NADPH + p-Nitrobenzaldehyde <-> NADP+ + p-Nitrobenzyl alcohol
H+ + NADPH + Prostaglandin H2 <-> NADP+ + Prostaglandin F2alpha
H+ + NADPH + Prostaglandin D2 <-> NADP+ + 9alpha,11beta-Prostaglandin F2
H+ + NADPH + 9,10-Phenanthroquinone <-> NADP+ + Phenanthrene-9,10-diol
H+ + NADPH + Prostaglandin D2 <-> NADP+ + Prostaglandin F2
H+ + NADPH + Phenylglyoxal <-> Unknown + NADP+
H+ + NADPH + Hydrindantin <-> Unknown + NADP+
H+ + NADPH + Prostaglandin J2 <-> Unknown + NADP+
H+ + NADPH + delta-12-13,14-Dihydro-prostaglandin J2 <-> Unknown + NADP+
H+ + NADPH + Prostaglandin A2 <-> Unknown + NADP+
H+ + NADPH + 4-Nitroacetophenone <-> NADP+ + 1-(4-Nitrophenyl)ethanol
H+ + NADPH + Cyclohexanone <-> NADP+ + Cyclohexanol
H+ + NADPH + Daunorubicin <-> Unknown + NADP+
H+ + NADPH + Menadione <-> NADP+ + Menadiol
H+ + NADPH + Phenylglyoxal <-> NADP+ + 2-Hydroxyacetophenone
H+ + NADPH + Duroquinone <-> NADP+ + Duroquinol
NADH + H+ + Hydrindantin <-> Unknown + NAD+
NADH + H+ + p-Nitrobenzaldehyde <-> NAD+ + p-Nitrobenzyl alcohol
H+ + NADPH + 5beta-Androstane-17beta-ol-3-one <-> NADP+ + Androstanediol
NADH + H+ + Menadione <-> NAD+ + Menadiol
NADH + H+ + Phenylglyoxal <-> NAD+ + 2-Hydroxyacetophenone
NADH + H+ + 9,10-Phenanthroquinone <-> NAD+ + Phenanthrene-9,10-diol
H+ + NADPH + Ubiquinone-10 <-> NADP+ + Ubiquinol
H+ + NADPH + Prostaglandin D1 <-> NADP+ + Prostaglandin F1alpha
NADH + H+ + 4-Nitroacetophenone <-> NAD+ + 1-(4-Nitrophenyl)ethanol
H+ + NADPH + Prostaglandin D3 <-> NADP+ + Prostaglandin F3alpha
NADH + H+ + Prostaglandin D2 <-> NAD+ + 9alpha,11beta-Prostaglandin F2
 External links Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop


View all entries for EC Class: 1.1.1.188



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