Enzyme Details

EC Classification

1.1.1.211

Enzyme name
(recommended)

long-chain-3-hydroxyacyl-CoA dehydrogenase

Alternative names

long-chain-(S)-3-hydroxyacyl-CoA:NAD+ oxidoreductase
beta-hydroxyacyl-CoA dehydrogenase
long-chain 3-hydroxyacyl coenzyme A dehydrogenase
3-hydroxyacyl-CoA dehydrogenase
LCHAD

Classification

Oxidoreductases

Acting on the CH-OH group of donors

With NAD(+) or NADP(+) as acceptor

Catalyses reactions

NAD+ + (3S)-3-Hydroxyacyl-CoA <-> NADH + H+ + 3-Oxoacyl-CoA

NAD+ + (S)-3-Hydroxyhexadecanoyl-CoA <-> NADH + H+ + 3-Oxopalmitoyl-CoA

NAD+ + (S)-3-Hydroxytetradecanoyl-CoA <-> NADH + H+ + 3-Oxotetradecanoyl-CoA

NAD+ + (S)-3-Hydroxydodecanoyl-CoA <-> NADH + H+ + 3-Oxododecanoyl-CoA

NAD+ + (S)-3-Hydroxydecanoyl-CoA <-> NADH + H+ + 3-Oxodecanoyl-CoA

NAD+ + (S)-3-Hydroxyoctanoyl-CoA <-> NADH + H+ + 3-Oxooctanoyl-CoA

NAD+ + (S)-3-Hydroxyhexanoyl-CoA <-> NADH + H+ + 3-Oxohexanoyl-CoA

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 1.1.1.211