Enzyme Details

 EC Classification 1.1.1.218
 Enzyme name
(recommended)		 morphine 6-dehydrogenase
 Alternative names morphine:NAD(P)+ 6-oxidoreductase
naloxone reductase
reductase, naloxone
 Classification
Oxidoreductases
Acting on the CH-OH group of donors
With NAD(+) or NADP(+) as acceptor
 Catalyses reactions
NAD+ + Morphine <-> NADH + H+ + Morphinone
NADP+ + Morphine <-> H+ + NADPH + Morphinone
NADP+ + Codeine <-> H+ + NADPH + 7,8-Didehydro-4,5-epoxy-3-methoxy-17-methoxy-(5_)-morphinan-6-one
NAD+ + Normorphine <-> NADH + H+ + Normorphinone
NAD+ + Ethylmorphine <-> NADH + H+ + Ethylmorphinone
NAD+ + Nalorphine <-> NADH + H+ + Nalorphinone
NAD+ + Dihydrocodeine <-> NADH + H+ + Hydrocodone
NAD+ + Codeine <-> NADH + H+ + 7,8-Didehydro-4,5-epoxy-3-methoxy-17-methoxy-(5_)-morphinan-6-one
NADP+ + Ethylmorphine <-> H+ + NADPH + Ethylmorphinone
NADP+ + Dihydrocodeine <-> H+ + NADPH + Hydrocodone
NADP+ + Nalorphine <-> H+ + NADPH + Nalorphinone
NADP+ + Normorphine <-> H+ + NADPH + Normorphinone
 External links Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop


View all entries for EC Class: 1.1.1.218



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