Enzyme Details

EC Classification

1.1.1.267

Enzyme name
(recommended)

1-deoxy-D-xylulose-5-phosphate reductoisomerase

Alternative names

2-C-methyl-D-erythritol-4-phosphate:NADP+ oxidoreductase (isomerizing)
DXP-reductoisomerase
1-deoxy-D-xylulose-5-phosphate isomeroreductase
2-C-methyl-D-erythritol 4-phosphate (MEP) synthase

Classification

Oxidoreductases

Acting on the CH-OH group of donors

With NAD(+) or NADP(+) as acceptor

Catalyses reactions

NADP+ + 2-C-Methyl-D-erythritol 4-phosphate <-> H+ + NADPH + 1-Deoxy-D-xylulose 5-phosphate

H+ + NADPH + 1-Fluoro-1-deoxy-D-xylulose 5-phosphate <-> NADP+ + 2-C-Fluoromethyl-D-erythritol 4-phosphate

H+ + NADPH + 1,2-Dideoxy-D-hexulose 6-phosphate <-> NADP+ + 2-C-Ethyl-D-erythritol 4-phosphate

H+ + NADPH + 1,1-Difluoro-1-deoxy-D-xylulose 5-phosphate <-> NADP+ + 2-C-Difluoromethyl-D-erythritol 4-phosphate

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 1.1.1.267