EC Classification |
1.1.1.49
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Enzyme name (recommended) |
glucose-6-phosphate dehydrogenase |
Alternative names |
D-glucose-6-phosphate:NADP+ 1-oxidoreductase
NADP-glucose-6-phosphate dehydrogenase
Zwischenferment
D-glucose 6-phosphate dehydrogenase
glucose 6-phosphate dehydrogenase (NADP)
NADP-dependent glucose 6-phosphate dehydrogenase
6-phosphoglucose dehydrogenase
Entner-Doudoroff enzyme
glucose-6-phosphate 1-dehydrogenase
G6PDH
GPD
|
Classification |
Oxidoreductases |
Acting on the CH-OH group of donors |
With NAD(+) or NADP(+) as acceptor |
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Catalyses reactions
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NADP+ + beta-D-Glucose 6-phosphate <-> H+ + NADPH + 6-Phospho-D-glucono-1,5-lactone |
NADP+ + D-Glucose 6-phosphate <-> H+ + NADPH + 6-Phospho-D-glucono-1,5-lactone |
NADP+ + Glucose 6-phosphate <-> H+ + NADPH + 6-Phospho-D-glucono-1,5-lactone |
Glucose 6-phosphate + thio-NADP+ <-> H+ + 6-Phospho-D-glucono-1,5-lactone + thio-NADPH |
Glucose 6-phosphate + thio-NAD+ <-> H+ + 6-Phospho-D-glucono-1,5-lactone + thio-NADH |
NADP+ + D-Galactose 6-phosphate <-> H+ + NADPH + 6-Phospho-D-galactono-1,5-lactone |
NADP+ + 2-Deoxy-D-glucose 6-phosphate <-> H+ + NADPH + 2-Deoxy-6-phospho-D-glucono-1,5-lactone |
NAD+ + Glucose 6-phosphate <-> NADH + H+ + 6-Phospho-D-glucono-1,5-lactone |
NAD+ + D-Glucose 6-phosphate <-> NADH + H+ + 6-Phospho-D-glucono-1,5-lactone |
NAD+ + D-Galactose 6-phosphate <-> NADH + H+ + 6-Phospho-D-galactono-1,5-lactone |
NAD+ + 2-Deoxy-D-glucose 6-phosphate <-> NADH + H+ + 2-Deoxy-6-phospho-D-glucono-1,5-lactone |
NADP+ + 6-Aminoglucose 6-phosphate <-> H+ + NADPH + 6-Aminoglucono-1,5-lactone |
NADP+ + sn-Glycerol 3-phosphate <-> Glycerone phosphate + H+ + NADPH |
Glucose 6-phosphate + Nicotinamide hypoxanthine dinucleotide phosphate <-> H+ + 6-Phospho-D-glucono-1,5-lactone + deamino-NADPH |
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External links
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Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop
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View all entries for EC Class:
1.1.1.49
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