Enzyme Details

EC Classification

1.1.3.15

Enzyme name
(recommended)

(S)-2-hydroxy-acid oxidase

Alternative names

(S)-2-hydroxy-acid:oxygen 2-oxidoreductase
glycolate oxidase
hydroxy-acid oxidase A
hydroxy-acid oxidase B
glycolate oxidase
oxidase, L-2-hydroxy acid
hydroxyacid oxidase A
L-alpha-hydroxy acid oxidase
L-2-hydroxy acid oxidase

Classification

Oxidoreductases

Acting on the CH-OH group of donors

With oxygen as acceptor

Catalyses reactions

O2 + Glycolate <-> Glyoxylate + H2O2

Glycolate + Acceptor <-> Glyoxylate + Reduced acceptor

O2 + (S)-2-Hydroxy acid <-> H2O2 + 2-Oxo acid

(S)-Mandelate + Acceptor <-> Reduced acceptor + alpha-Oxo-benzeneacetic acid

O2 + Phenyllactate <-> H2O2 + Phenylpyruvate

O2 + (S)-Mandelate <-> H2O2 + alpha-Oxo-benzeneacetic acid

O2 + 2-Hydroxybutyrate <-> H2O2 + 2-Oxobutyrate

O2 + L-2-Hydroxyisocaproate <-> H2O2 + 4-Methyl-2-oxopentanoate

O2 + L-Lactate <-> Pyruvate + H2O2

O2 + Methionine <-> Unknown + H2O2

O2 + 2-Hydroxyvalerate <-> H2O2 + 2-Oxopentanoate

O2 + 2-Hydroxycaproate <-> H2O2 + 2-Oxohexanoate

O2 + 3-Chlorolactate <-> Unknown + H2O2

L-Leucine + O2 <-> Unknown + H2O2

L-Tryptophan + O2 <-> Unknown + H2O2

O2 + (S)-2-Hydroxyisovalerate <-> H2O2 + alpha-Ketovaline

O2 + 3-Chlorolactate <-> H2O2 + 3-Chloropyruvate

O2 + (S)-3-(4-Hydroxyphenyl)lactate <-> H2O2 + 3-(4-Hydroxyphenyl)pyruvate

L-Lactate + Acceptor <-> Pyruvate + Reduced acceptor

O2 + (S)-2-Hydroxyglutarate <-> H2O2 + 2-Oxoglutarate

(S)-2-Hydroxyglutarate + L-2-Hydroxyglutarate oxidase <-> Enzyme-ligand complex

Sulfite + L-2-Hydroxyglutarate oxidase <-> Enzyme-ligand complex

H2O + O2 + Glyoxylate <-> H2O2 + Oxalate

O2 + 2-Hydroxyoctanoate <-> H2O2 + 2-Oxooctanoate

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 1.1.3.15