Enzyme Details

EC Classification

1.1.99.36

Enzyme name
(recommended)

NDMA-dependent alcohol dehydrogenase

Alternative names

ethanol:N,N-dimethyl-4-nitrosoaniline oxidoreductase
nicotinoprotein alcohol dehydrogenase
np-ADH

Classification

Oxidoreductases

Acting on the CH-OH group of donors

With other acceptors

Catalyses reactions

Ethanol + N,N-Dimethyl-4-nitrosoaniline <-> Acetaldehyde + 4-(Hydroxylamino)-N,N-dimethylaniline

1-Propanol + N,N-Dimethyl-4-nitrosoaniline <-> Propanal + 4-(Hydroxylamino)-N,N-dimethylaniline

1-Butanol + N,N-Dimethyl-4-nitrosoaniline <-> Benzaldehyde + 4-(Hydroxylamino)-N,N-dimethylaniline

1-Pentanol + N,N-Dimethyl-4-nitrosoaniline <-> 1-Pentanal + 4-(Hydroxylamino)-N,N-dimethylaniline

1-Hexanol + N,N-Dimethyl-4-nitrosoaniline <-> Hexanal + 4-(Hydroxylamino)-N,N-dimethylaniline

Heptanol + N,N-Dimethyl-4-nitrosoaniline <-> Heptanal + 4-(Hydroxylamino)-N,N-dimethylaniline

1-Octanol + N,N-Dimethyl-4-nitrosoaniline <-> 1-Octanal + 4-(Hydroxylamino)-N,N-dimethylaniline

2-Propen-1-ol + N,N-Dimethyl-4-nitrosoaniline <-> Acrolein + 4-(Hydroxylamino)-N,N-dimethylaniline

Isobutanol + N,N-Dimethyl-4-nitrosoaniline <-> 4-(Hydroxylamino)-N,N-dimethylaniline + Isobutanal

3-Methylbutanol + N,N-Dimethyl-4-nitrosoaniline <-> 3-Methylbutanal + 4-(Hydroxylamino)-N,N-dimethylaniline

N,N-Dimethyl-4-nitrosoaniline + Citronellol <-> 4-(Hydroxylamino)-N,N-dimethylaniline + Citronellal

Benzyl alcohol + N,N-Dimethyl-4-nitrosoaniline <-> Benzaldehyde + 4-(Hydroxylamino)-N,N-dimethylaniline

p-Hydroxybenzyl alcohol + N,N-Dimethyl-4-nitrosoaniline <-> 4-Hydroxybenzaldehyde + 4-(Hydroxylamino)-N,N-dimethylaniline

4-Hydroxy-3-methoxy-benzenemethanol + N,N-Dimethyl-4-nitrosoaniline <-> 4-Hydroxy-3-methoxy-benzaldehyde + 4-(Hydroxylamino)-N,N-dimethylaniline

Veratryl alcohol + N,N-Dimethyl-4-nitrosoaniline <-> Veratraldehyde + 4-(Hydroxylamino)-N,N-dimethylaniline

Phenylethyl alcohol + N,N-Dimethyl-4-nitrosoaniline <-> Phenylacetaldehyde + 4-(Hydroxylamino)-N,N-dimethylaniline

N,N-Dimethyl-4-nitrosoaniline + 2-Phenylpropanol <-> 2-Phenylpropionaldehyde + 4-(Hydroxylamino)-N,N-dimethylaniline

3-Phenyl-1-propanol + N,N-Dimethyl-4-nitrosoaniline <-> 4-(Hydroxylamino)-N,N-dimethylaniline + 3-Phenylpropionaldehyde

N,N-Dimethyl-4-nitrosoaniline + 3-(4-Hydroxyphenyl)-1-propanol <-> 4-(Hydroxylamino)-N,N-dimethylaniline + 3-(4-Hydroxyphenyl)propanal

Cinnamyl alcohol + N,N-Dimethyl-4-nitrosoaniline <-> Cinnamaldehyde + 4-(Hydroxylamino)-N,N-dimethylaniline

Coniferyl alcohol + N,N-Dimethyl-4-nitrosoaniline <-> Coniferaldehyde + 4-(Hydroxylamino)-N,N-dimethylaniline

N,N-Dimethyl-4-nitrosoaniline + 2-Phenylbutan-1-ol <-> 4-(Hydroxylamino)-N,N-dimethylaniline + 2-Phenylbutyraldehyde

N,N-Dimethyl-4-nitrosoaniline + 4-(4-Methoxyphenyl)butan-1-ol <-> 4-(Hydroxylamino)-N,N-dimethylaniline + 4-(4-Methoxyphenyl)butanal

2-Propanol + N,N-Dimethyl-4-nitrosoaniline <-> Acetone + 4-(Hydroxylamino)-N,N-dimethylaniline

2-Butanol + N,N-Dimethyl-4-nitrosoaniline <-> 2-Butanone + 4-(Hydroxylamino)-N,N-dimethylaniline

2-Pentanol + N,N-Dimethyl-4-nitrosoaniline <-> 2-Pentanone + 4-(Hydroxylamino)-N,N-dimethylaniline

2-Hexanol + N,N-Dimethyl-4-nitrosoaniline <-> 2-Hexanone + 4-(Hydroxylamino)-N,N-dimethylaniline

Heptan-2-ol + N,N-Dimethyl-4-nitrosoaniline <-> Heptan-2-one + 4-(Hydroxylamino)-N,N-dimethylaniline

N,N-Dimethyl-4-nitrosoaniline + Octan-2-ol <-> Octan-2-one + 4-(Hydroxylamino)-N,N-dimethylaniline

N,N-Dimethyl-4-nitrosoaniline + 3-Methylheptan-4-ol <-> 4-(Hydroxylamino)-N,N-dimethylaniline + 3-Methylheptan-4-one

N,N-Dimethyl-4-nitrosoaniline + 4-Methylheptan-3-ol <-> 4-(Hydroxylamino)-N,N-dimethylaniline + 4-Methylheptan-3-one

1-Phenylethanol + N,N-Dimethyl-4-nitrosoaniline <-> Acetophenone + 4-(Hydroxylamino)-N,N-dimethylaniline

N,N-Dimethyl-4-nitrosoaniline + 1-Phenylpropan-1-ol <-> 4-(Hydroxylamino)-N,N-dimethylaniline + 1-Phenylpropan-1-one

N,N-Dimethyl-4-nitrosoaniline + 1-Phenylpropan-2-ol <-> 4-(Hydroxylamino)-N,N-dimethylaniline + 1-Phenylpropan-2-one

N,N-Dimethyl-4-nitrosoaniline + 1-Phenylbutan-2-ol <-> 4-(Hydroxylamino)-N,N-dimethylaniline + 1-Phenylbutan-2-one

Cyclohexanol + N,N-Dimethyl-4-nitrosoaniline <-> Cyclohexanone + 4-(Hydroxylamino)-N,N-dimethylaniline

1,2-Propanediol + N,N-Dimethyl-4-nitrosoaniline <-> Methylglyoxal + 4-(Hydroxylamino)-N,N-dimethylaniline

1,3-Propanediol + N,N-Dimethyl-4-nitrosoaniline <-> 3-Hydroxypropanal + 4-(Hydroxylamino)-N,N-dimethylaniline

N,N-Dimethyl-4-nitrosoaniline + 3-Butene-1,2-diol <-> Unknown + 4-(Hydroxylamino)-N,N-dimethylaniline

N,N-Dimethyl-4-nitrosoaniline + 1,2-Pentanediol <-> Unknown + 4-(Hydroxylamino)-N,N-dimethylaniline

N,N-Dimethyl-4-nitrosoaniline + 1-Phenylethane-1,2-diol <-> Unknown + 4-(Hydroxylamino)-N,N-dimethylaniline

Formaldehyde + N,N-Dimethyl-4-nitrosoaniline <-> Methanol + 4-(Hydroxylamino)-N,N-dimethylaniline

Acetaldehyde + Veratryl alcohol <-> Ethanol + Veratraldehyde

Benzaldehyde + Veratryl alcohol <-> Benzyl alcohol + Veratraldehyde

Veratryl alcohol + 2-Phenylpropionaldehyde <-> Veratraldehyde + 2-Phenylpropanol

Veratryl alcohol + 3-Phenylpropionaldehyde <-> Veratraldehyde + 3-Phenyl-1-propanol

Veratryl alcohol + 3-Phenylbutanal <-> Veratraldehyde + 3-Phenylbutan-1-ol

Veratryl alcohol + Glyoxal <-> Glycolaldehyde + Veratraldehyde

Methylglyoxal + Veratryl alcohol <-> Hydroxyacetone + Veratraldehyde

Veratryl alcohol + Phenylglyoxal <-> Veratraldehyde + 2-Hydroxyacetophenone

Hydroxyacetone + Veratryl alcohol <-> 1,2-Propanediol + Veratraldehyde

Cyclohexanone + Veratryl alcohol <-> Cyclohexanol + Veratraldehyde

External links

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