Enzyme Details

EC Classification

1.11.1.12

Enzyme name
(recommended)

phospholipid-hydroperoxide glutathione peroxidase

Alternative names

phospholipid hydroperoxide glutathione peroxidase
glutathione:lipid-hydroperoxide oxidoreductase
peroxidation-inhibiting protein
PHGPX
peroxidation-inhibiting protein: peroxidase, glutathione (phospholipid hydroperoxide-reducing)
hydroperoxide glutathione peroxidase

Classification

Oxidoreductases

Acting on a peroxide as acceptor (peroxidases)

Peroxidase

Catalyses reactions

2 Reduced glutathione + Lipid hydroperoxide <-> 2 H2O + Oxidized glutathione + Lipid

2 Reduced glutathione + (beta-(13-Hydroperoxy-cis-9, trans-11-octadecadienoyl)-gamma-palmitoyl)-L-alpha-phosphatidylcholine <-> Unknown + 2 H2O + Oxidized glutathione

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 1.11.1.12