Enzyme Details

EC Classification

1.14.11.1

Enzyme name
(recommended)

gamma-butyrobetaine dioxygenase

Alternative names

4-trimethylammoniobutanoate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)
alpha-butyrobetaine hydroxylase
gamma-butyrobetaine hydroxylase
butyrobetaine hydroxylase

Classification

Oxidoreductases

Acting on paired donors with incorporation of molecular oxygen

With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor

Catalyses reactions

O2 + 2-Oxoglutarate + 4-Trimethylammoniobutanoate <-> CO2 + Succinate + Carnitine

3-Dehydroxycarnitine <-> Carnitine

O2 + 2-Oxoglutarate + 4-Trimethylammoniobutanoate <-> CO2 + L-Carnitine + Succinate

O2 + 4-Trimethylammoniobutanoate + 3-Bromo-2-ketoglutarate <-> CO2 + L-Carnitine + 3-Bromo-succinate

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 1.14.11.1