Enzyme Details

EC Classification

1.14.11.11

Enzyme name
(recommended)

hyoscyamine (6S)-dioxygenase

Alternative names

L-hyoscyamine,2-oxoglutarate:oxygen oxidoreductase ((6S)-hydroxylating)
hyoscyamine 6beta-hydroxylase
hyoscyamine 6beta-dioxygenase
hyoscyamine 6-hydroxylase

Classification

Oxidoreductases

Acting on paired donors with incorporation of molecular oxygen

With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor

Catalyses reactions

O2 + 2-Oxoglutarate + L-Hyoscyamine <-> H2O + CO2 + Succinate + (6S)-Hydroxyhyoscyamine

O2 + 2-Oxoglutarate + L-Hyoscyamine <-> CO2 + Succinate + (6S)-Hydroxyhyoscyamine

O2 + 2-Oxoglutarate + 6,7-Dehydrohyoscyamine <-> CO2 + Succinate + Scopolamine

O2 + 2-Oxoglutarate + (6S)-Hydroxyhyoscyamine <-> H2O + CO2 + Succinate + Scopolamine

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 1.14.11.11