Enzyme Details

 EC Classification 1.14.12.17
 Enzyme name
(recommended)
nitric oxide dioxygenase
 Alternative names nitric oxide,NAD(P)H:oxygen oxidoreductase
 Classification
Oxidoreductases
Acting on paired donors with incorporation of molecular oxygen
With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor
 Catalyses reactions
NADH + H+ + H2O2 <-> NAD+ + 2 H2O
NADH + 2 O2 + 2 Nitric oxide <-> NAD+ + H+ + 2 Nitrate
NADPH + 2 O2 + 2 Nitric oxide <-> H+ + NADP+ + 2 Nitrate
NADH + H+ + Cumene hydroperoxide <-> NAD+ + H2O + 2-Phenyl-2-propanol
NADH + H+ + t-Butylhydroperoxide <-> NAD+ + H2O + t-Butanol
NADH + H+ + (9Z,11E)-(13S)-13-Hydroperoxyoctadeca-9,11-dienoate <-> NAD+ + H2O + 13(S)-HODE
NAD+ + 2 Fe2+ <-> NADH + H+ + 2 Fe3+
NADH + S-Nitrosoglutathione <-> NAD+ + Glutathione sulfinamide
NADH + H+ + Cytochrome c <-> NAD+ + Reduced cytochrome c
NADH + H+ + Nitrite <-> NAD+ + H2O + Nitric oxide
 External links Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop


View all entries for EC Class: 1.14.12.17



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