Enzyme Details

EC Classification

1.14.13.22

Enzyme name
(recommended)

cyclohexanone monooxygenase

Alternative names

cyclohexanone,NADPH:oxygen oxidoreductase (lactone-forming)
cyclohexanone 1,2-monooxygenase
cyclohexanone oxygenase
cyclohexanone:NADPH:oxygen oxidoreductase (6-hydroxylating, 1,2-lactonizing)

Classification

Oxidoreductases

Acting on paired donors with incorporation of molecular oxygen

With NADH or NADPH as one donor, and incorporation of one atom of oxygen

Catalyses reactions

H+ + NADPH + O2 + Cyclohexanone <-> H2O + NADP+ + 6-Hexanolide

H+ + NADPH + 2-Hydroxycyclohexan-1-one <-> NADP+ + 1-Oxa-2-oxo-3-hydroxycycloheptane

NADH + H+ + O2 + Cyclohexanone <-> NAD+ + H2O + 6-Hexanolide

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 1.14.13.22