Enzyme Details

 EC Classification 1.14.13.9
 Enzyme name
(recommended)		 kynurenine 3-monooxygenase
 Alternative names L-kynurenine,NADPH:oxygen oxidoreductase (3-hydroxylating)
kynurenine 3-hydroxylase
kynurenine hydroxylase
L-kynurenine-3-hydroxylase
 Classification
Oxidoreductases
Acting on paired donors with incorporation of molecular oxygen
With NADH or NADPH as one donor, and incorporation of one atom of oxygen
 Catalyses reactions
H+ + NADPH + O2 + L-Kynurenine <-> H2O + NADP+ + 3-Hydroxy-L-kynurenine
NADH + H+ + O2 + L-Kynurenine <-> NAD+ + H2O + 3-Hydroxy-L-kynurenine
L-Kynurenine + KMO-FAD <-> Enzyme-FAD-L-Kynurenine complex
KMO-FAD + m-Nitrobenzoylalanine <-> Enzyme-FAD-m-Nitrobenzoylalanine complex
 External links Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop


View all entries for EC Class: 1.14.13.9



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