Enzyme Details

 EC Classification 1.14.14.16
 Enzyme name
(recommended)		 steroid 21-monooxygenase
 Classification
Oxidoreductases
Acting on paired donors with incorporation of molecular oxygen
With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
 Catalyses reactions
H+ + NADPH + O2 + Progesterone <-> H2O + NADP+ + 11-Deoxycorticosterone
NADPH + O2 + 17alpha-Hydroxyprogesterone <-> H+ + H2O + NADP+ + 11-Deoxycortisol
Progesterone + CYP21A2 <-> Enzyme-ligand complex
17alpha-Hydroxyprogesterone + CYP21A2 <-> Enzyme-ligand complex
11-Deoxycorticosterone + CYP21A2 <-> Enzyme-ligand complex
11-Deoxycortisol + CYP21A2 <-> Enzyme-ligand complex
 External links Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop


View all entries for EC Class: 1.14.14.16



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