Enzyme Details
EC Classification
1.14.14.55
Enzyme name
(recommended)
quinine 3-monooxygenase
Alternative names
quinine,NADPH:oxygen oxidoreductase
quinine 3-hydroxylase
Classification
Oxidoreductases
Acting on paired donors with incorporation of molecular oxygen
With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
Catalyses reactions
H+ + NADPH + O2 + Quinine <-> H2O + NADP+ + 3-Hydroxyquinine
H+ + NADPH + O2 + 7-Benzyloxyquinoline <-> H2O + NADP+ + Benzaldehyde + 7-Hydroxyquinoline
H+ + NADPH + O2 + Testosterone <-> H2O + NADP+ + 15beta-Hydroxytestosterone
H+ + NADPH + O2 + Testosterone <-> H2O + NADP+ + 1beta-Hydroxytestosterone
H+ + NADPH + O2 + Testosterone <-> H2O + NADP+ + 2beta-Hydroxytestosterone
H+ + NADPH + O2 + Testosterone <-> H2O + NADP+ + 6beta-Hydroxytestosterone
H+ + NADPH + O2 + Carbamazepine <-> H2O + NADP+ + Carbamazepine-10,11-epoxide
H+ + NADPH + O2 + Nevirapine <-> H2O + NADP+ + 2-Hydroxy-nevirapine
NADPH + O2 + Pradefovir <-> H2O + NADP+ + Adefovir
External links
Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop
View all entries for EC Class:
1.14.14.55
© HITS gGmbH
