Enzyme Details

EC Classification

1.14.14.92

Enzyme name
(recommended)

benzoate 4-monooxygenase

Classification

Oxidoreductases

Acting on paired donors with incorporation of molecular oxygen

With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

Catalyses reactions

H+ + NADPH + O2 + Benzoate <-> H2O + NADP+ + 4-Hydroxybenzoate

H+ + NADPH + O2 + 2-Fluorobenzoate <-> H2O + NADP+ + 2-Fluoro-4-hydroxybenzoic acid

H+ + NADPH + O2 + 2-Chlorobenzoate <-> H2O + NADP+ + 2-Chloro-4-hydroxybenzoic acid

H+ + NADPH + O2 + Salicylate <-> H2O + NADP+ + 2,4-Dihydroxybenzoate

H+ + NADPH + O2 + o-Toluate <-> H2O + NADP+ + 4-Hydroxy-2-methylbenzoic acid

H+ + NADPH + O2 + 3-Fluorobenzoate <-> H2O + NADP+ + 3-Fluoro-4-hydroxybenzoic acid

H+ + NADPH + O2 + 3-Chlorobenzoate <-> H2O + NADP+ + 3-Chloro-4-hydroxybenzoic acid

H+ + NADPH + O2 + m-Methylbenzoate <-> H2O + NADP+ + 4-Hydroxy-3-methylbenzoic acid

3 H+ + 3 NADPH + 3 O2 + m-Methoxybenzoate <-> 4 H2O + 3 NADP+ + Formate + 3-Hydroxybenzoate

Benzoate + CYP53A1 <-> Enzyme-ligand complex

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 1.14.14.92

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