Enzyme Details

EC Classification

1.14.18.2

Enzyme name
(recommended)

CMP-N-acetylneuraminate monooxygenase

Alternative names

CMP-N-acetylneuraminate,ferrocytochrome-b5:oxygen oxidoreductase (N-acetyl-hydroxylating)
CMP-N-acetylneuraminic acid hydroxylase
CMP-Neu5Ac hydroxylase
cytidine monophosphoacetylneuraminate monooxygenase
N-acetylneuraminic monooxygenase
cytidine-5'-monophosphate-N-acetylneuraminic acid hydroxylase

Classification

Oxidoreductases

Acting on paired donors with incorporation of molecular oxygen

With another compound as one donor, and incorporation of one atom of oxygen

Catalyses reactions

NADH + H+ + O2 + CMP-N-acetylneuraminate <-> NAD+ + H2O + CMP-N-glycoloylneuraminate

H+ + NADPH + O2 + CMP-N-acetylneuraminate <-> H2O + NADP+ + CMP-N-glycoloylneuraminate

2 H+ + O2 + 2 Ferrocytochrome b5 + CMP-N-acetylneuraminate <-> H2O + 2 Ferricytochrome b5 + CMP-N-glycoloylneuraminate

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 1.14.18.2