Enzyme Details

EC Classification

1.14.18.8

Enzyme name
(recommended)

7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase

Alternative names

7alpha-hydroxycholest-4-en-3-one,NADPH:oxygen oxidoreductase (12alpha-hydroxylating)
7alpha-hydroxy-4-cholesten-3-one 12alpha-monooxygenase
CYP12
sterol 12alpha-hydroxylase (ambiguous)
HCO 12alpha-hydroxylase

Classification

Oxidoreductases

Acting on paired donors with incorporation of molecular oxygen

With another compound as one donor, and incorporation of one atom of oxygen

Catalyses reactions

H+ + NADPH + O2 + 7alpha-Hydroxycholest-4-en-3-one <-> H2O + NADP+ + 7alpha,12alpha-Dihydroxycholest-4-en-3-one

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 1.14.18.8