Enzyme Details

EC Classification

1.16.1.8

Enzyme name
(recommended)

[methionine synthase] reductase

Alternative names

[methionine synthase]-methylcob(I)alamin,S-adenosylhomocysteine:NADP+ oxidoreductase
methionine synthase cob(II)alamin reductase (methylating)
methionine synthase reductase
[methionine synthase]-cobalamin methyltransferase (cob(II)alamin reducing)

Classification

Oxidoreductases

Oxidizing metal ions

With NAD(+) or NADP(+) as acceptor

Catalyses reactions

H+ + NADPH + S-Adenosyl-L-methionine + [Methionine synthase]-cob(II)alamin <-> NADP+ + S-Adenosyl-L-homocysteine + [Methionine synthase]-methylcob(I)alamin

H+ + NADPH + 2 Ferricytochrome c <-> NADP+ + 2 Ferrocytochrome c

NADH + Cytochrome c3+ <-> NAD+ + H+ + Cytochrome c2+

NADPH + Cytochrome c3+ <-> H+ + NADP+ + Cytochrome c2+

NADP+ + MSR <-> Enzyme-ligand complex

Adenosine 2',5'-bisphosphate + MSR <-> Enzyme-ligand complex

Adenosine 2',5'-bisphosphate + FADD <-> Enzyme-ligand complex

NADP+ + FADD <-> Enzyme-ligand complex

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 1.16.1.8