Enzyme Details

EC Classification

1.2.1

Enzyme name
(recommended)

With NAD(+) or NADP(+) as acceptor

Classification

Oxidoreductases

Acting on the aldehyde or oxo group of donors

With NAD(+) or NADP(+) as acceptor

Catalyses reactions

NAD+ + H2O + Glycolaldehyde <-> NADH + H+ + Glycolate

NAD+ + H2O + Acetaldehyde <-> NADH + H+ + Acetate

NAD+ + H2O + D-Erythrose 4-phosphate <-> NADH + H+ + 4-Phospho-D-erythronate

NAD+ + H2O + 4-Aminobutanal <-> NADH + H+ + 4-Aminobutanoate

NAD+ + (R)-Mandelate <-> NADH + H+ + alpha-Oxo-benzeneacetic acid

H+ + NADPH + L-Glutamyl-tRNA(Glu) <-> H2O + NADP+ + tRNA(Glu) + (S)-4-Amino-5-oxopentanoate

NAD+ + H2O + 2-Hydroxy-5-carboxymethylmuconate semialdehyde <-> NADH + H+ + 5-Carboxymethyl-2-hydroxymuconate

NAD+ + H2O + 5-(2'-Formylethyl)-4,6-dihydroxypicolinate <-> NADH + H+ + 5-(2'-Carboxyethyl)-4,6-dihydroxypicolinate

H2O + NADP+ + 5-(2'-Formylethyl)-4,6-dihydroxypicolinate <-> H+ + NADPH + 5-(2'-Carboxyethyl)-4,6-dihydroxypicolinate

NAD+ + H2O + 2-Carboxybenzaldehyde <-> NADH + H+ + Phthalate

NAD+ + H2O + 1-Hydroxy-2-naphthaldehyde <-> NADH + H+ + 1-Hydroxy-2-naphthoate

NAD+ + H2O + (Z)-2-Methyl-5-isopropylhexa-2,5-dienal <-> NADH + H+ + cis-2-Methyl-5-isopropylhexa-2,5-dienoic acid

NAD+ + H2O + trans-2-Methyl-5-isopropylhexa-2,5-dienal <-> NADH + H+ + trans-2-Methyl-5-isopropylhexa-2,5-dienoic acid

H+ + NADPH + N2-Acetyl-L-aminoadipyl-delta-phosphate <-> Phosphate + NADP+ + N2-Acetyl-L-aminoadipate semialdehyde

NAD+ + H2O + Salicylaldehyde <-> NADH + H+ + Salicylate

NAD+ + H2O + Propanal <-> NADH + H+ + Propanoate

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 1.2.1

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