Enzyme Details

 EC Classification 1.2.1.18
 Enzyme name
(recommended)		 malonate-semialdehyde dehydrogenase (acetylating)
 Alternative names 3-oxopropanoate:NAD(P)+ oxidoreductase (decarboxylating, CoA-acetylating)
malonic semialdehyde oxidative decarboxylase
 Classification
Oxidoreductases
Acting on the aldehyde or oxo group of donors
With NAD(+) or NADP(+) as acceptor
 Catalyses reactions
NAD+ + Coenzyme A + 3-Oxopropanoate <-> NADH + H+ + CO2 + Acetyl-CoA
NADP+ + Coenzyme A + 3-Oxopropanoate <-> H+ + NADPH + CO2 + Acetyl-CoA
NADP+ + Coenzyme A + 3-Oxopropanoate <-> H+ + NADPH + Malonyl-CoA
NAD+ + Coenzyme A + (S)-Methylmalonate semialdehyde <-> NADH + H+ + (R)-2-Methyl-3-oxopropanoyl-CoA
 External links Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop


View all entries for EC Class: 1.2.1.18



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