Enzyme Details

EC Classification

1.2.1.19

Enzyme name
(recommended)

aminobutyraldehyde dehydrogenase

Alternative names

4-aminobutanal:NAD+ 1-oxidoreductase
gamma-guanidinobutyraldehyde dehydrogenase (ambiguous)
ABAL dehydrogenase
4-aminobutyraldehyde dehydrogenase
4-aminobutanal dehydrogenase
gamma-aminobutyraldehyde dehydroganase
1-pyrroline dehydrogenase
ABALDH
YdcW

Classification

Oxidoreductases

Acting on the aldehyde or oxo group of donors

With NAD(+) or NADP(+) as acceptor

Catalyses reactions

NAD+ + H2O + Glycolaldehyde <-> NADH + H+ + Glycolate

NAD+ + H2O + Methylglyoxal <-> Pyruvate + NADH + H+

H2O + NADP+ + Methylglyoxal <-> Pyruvate + H+ + NADPH

H2O + NADP+ + Acetaldehyde <-> H+ + NADPH + Acetate

NAD+ + H2O + Acetaldehyde <-> NADH + H+ + Acetate

NAD+ + H2O + Formaldehyde <-> NADH + H+ + Formate

NAD+ + H2O + Benzaldehyde <-> NADH + H+ + Benzoate

H2O + NADP+ + Benzaldehyde <-> H+ + NADPH + Benzoate

H2O + NADP+ + 4-Aminobutanal <-> H+ + NADPH + 4-Aminobutanoate

NAD+ + H2O + Phenylacetaldehyde <-> NADH + H+ + Phenylacetic acid

H2O + NADP+ + Phenylacetaldehyde <-> H+ + NADPH + Phenylacetic acid

NAD+ + H2O + 4-Aminobutanal <-> NADH + H+ + 4-Aminobutanoate

NAD+ + H2O + Betaine aldehyde <-> NADH + H+ + Betaine

H2O + NADP+ + Betaine aldehyde <-> H+ + NADPH + Betaine

NAD+ + H2O + Butanal <-> NADH + H+ + Butanoate

NAD+ + H2O + Glyceraldehyde <-> NADH + H+ + Glycerate

NAD+ + H2O + Pentanal <-> NADH + H+ + Pentanoate

H2O + NADP+ + Propanal <-> H+ + NADPH + Propanoate

NAD+ + H2O + p-Nitrobenzaldehyde <-> NADH + H+ + p-Nitrobenzoate

H2O + NADP+ + Glyceraldehyde <-> H+ + NADPH + Glycerate

NAD+ + H2O + Propanal <-> NADH + H+ + Propanoate

NAD+ + H2O + 3-Methylbutanal <-> NADH + H+ + Isovaleric acid

H2O + NADP+ + Glycolaldehyde <-> H+ + NADPH + Glycolate

H2O + NADP+ + Butanal <-> H+ + NADPH + Butanoate

H2O + NADP+ + Pentanal <-> H+ + NADPH + Pentanoate

H2O + NADP+ + 3-Methylbutanal <-> H+ + NADPH + Isovaleric acid

H2O + NADP+ + Undecanal <-> H+ + NADPH + Undecanoate

NAD+ + H2O + Undecanal <-> NADH + H+ + Undecanoate

H2O + NADP+ + p-Nitrobenzaldehyde <-> H+ + NADPH + p-Nitrobenzoate

NAD+ + 2 H2O + 1-Pyrroline <-> NADH + H+ + 4-Aminobutanoate

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 1.2.1.19

© HITS gGmbH