Enzyme Details

EC Classification

1.2.1.24

Enzyme name
(recommended)

succinate-semialdehyde dehydrogenase (NAD+)

Alternative names

succinate-semialdehyde:NAD+ oxidoreductase
succinate semialdehyde dehydrogenase (NAD+)
succinic semialdehyde dehydrogenase (NAD+)
succinyl semialdehyde dehydrogenase (NAD+)
succinate semialdehyde:NAD+ oxidoreductase

Classification

Oxidoreductases

Acting on the aldehyde or oxo group of donors

With NAD(+) or NADP(+) as acceptor

Catalyses reactions

NAD+ + H2O + Acetaldehyde <-> NADH + H+ + Acetate

NAD+ + H2O + L-Glutamate 5-semialdehyde <-> NADH + H+ + L-Glutamate

NAD+ + H2O + Succinate semialdehyde <-> NADH + H+ + Succinate

NAD+ + H2O + N2-Succinyl-L-glutamate 5-semialdehyde <-> NADH + H+ + N2-Succinyl-L-glutamate

NAD+ + H2O + Butanal <-> NADH + H+ + Butanoate

NAD+ + H2O + Pentanal <-> NADH + H+ + Pentanoate

NAD+ + H2O + p-Nitrobenzaldehyde <-> NADH + H+ + p-Nitrobenzoate

NADH + H+ + m-Nitrobenzaldehyde <-> NAD+ + m-Nitrobenzyl alcohol

NAD+ + H2O + Propanal <-> NADH + H+ + Propanoate

NAD+ + H2O + Succinate semialdehyde methyl ester <-> NADH + H+ + Methyl hydrogen succinate

NAD+ + H2O + trans-1-Formyl-cyclopropan-2-carboxylic acid <-> NADH + H+ + trans-1,2-Cyclopropanedicarboxylic acid

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 1.2.1.24