Enzyme Details

 EC Classification 1.2.1.26
 Enzyme name
(recommended)		 2,5-dioxovalerate dehydrogenase
 Alternative names 2,5-dioxopentanoate:NADP+ 5-oxidoreductase
2-oxoglutarate semialdehyde dehydrogenase
alpha-ketoglutaric semialdehyde dehydrogenase
 Classification
Oxidoreductases
Acting on the aldehyde or oxo group of donors
With NAD(+) or NADP(+) as acceptor
 Catalyses reactions
H2O + NADP+ + 2,5-Dioxopentanoate <-> H+ + NADPH + 2-Oxoglutarate
NAD+ + H2O + 2,5-Dioxopentanoate <-> NADH + H+ + 2-Oxoglutarate
H2O + NADP+ + Succinate semialdehyde <-> H+ + NADPH + Succinate
NAD+ + H2O + Succinate semialdehyde <-> NADH + H+ + Succinate
H2O + NADP+ + Propanal <-> H+ + NADPH + Propanoate
NAD+ + H2O + Propanal <-> NADH + H+ + Propanoate
H2O + NADP+ + Glutaral <-> H+ + NADPH + 5-Oxopentanoate
NAD+ + H2O + Glutaral <-> NADH + H+ + 5-Oxopentanoate
H2O + NADP+ + Acetaldehyde <-> H+ + NADPH + Acetate
 External links Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop


View all entries for EC Class: 1.2.1.26



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