Enzyme Details

EC Classification

1.2.1.31

Enzyme name
(recommended)

L-aminoadipate-semialdehyde dehydrogenase

Alternative names

(S)-2-amino-6-oxohexanoate:NAD(P)+ 6-oxidoreductase
aminoadipate semialdehyde dehydrogenase
2-aminoadipate semialdehyde dehydrogenase
alpha-aminoadipate-semialdehyde dehydrogenase
alpha-aminoadipate reductase
2-aminoadipic semialdehyde dehydrogenase
L-alpha-aminoadipate delta-semialdehyde oxidoreductase
L-alpha-aminoadipate delta-semialdehyde:NAD+ oxidoreductase
L-alpha-aminoadipate delta-semialdehyde:nicotinamide adenine dinucleotide oxidoreductase
L-2-aminoadipate 6-semialdehyde:NAD(P)+ 6-oxidoreductase

Classification

Oxidoreductases

Acting on the aldehyde or oxo group of donors

With NAD(+) or NADP(+) as acceptor

Catalyses reactions

ATP + L-2-Aminoadipate <-> Diphosphate + L-2-Aminoadipate adenylate

H2O + NADP+ + L-2-Aminoadipate 6-semialdehyde <-> H+ + NADPH + L-2-Aminoadipate

H+ + NADPH + alpha-Aminoadipoyl-S-acyl enzyme <-> NADP+ + L-2-Aminoadipate 6-semialdehyde + Holo-Lys2

L-2-Aminoadipate adenylate + Holo-Lys2 <-> AMP + alpha-Aminoadipoyl-S-acyl enzyme

NAD+ + H2O + L-2-Aminoadipate 6-semialdehyde <-> NADH + H+ + L-2-Aminoadipate

NAD+ + H2O + Acetaldehyde <-> NADH + H+ + Acetate

NAD+ + H2O + Propanal <-> NADH + H+ + Propanoate

NAD+ + H2O + Benzaldehyde <-> NADH + H+ + Benzoate

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 1.2.1.31