Enzyme Details

EC Classification

1.21.99.4

Enzyme name
(recommended)

thyroxine 5'-deiodinase

Alternative names

acceptor:3,5,3'-triiodo-L-thyronine oxidoreductase (iodinating)
diiodothyronine 5'-deiodinase
iodothyronine 5'-deiodinase
iodothyronine outer ring monodeiodinase
type I iodothyronine deiodinase
type II iodothyronine deiodinase
thyroxine 5-deiodinase
L-thyroxine iodohydrolase (reducing)

Classification

Oxidoreductases

Acting on X-H and Y-H to form an X-Y bond

With other acceptors

Catalyses reactions

L-Thyroxine + Reduced acceptor <-> H+ + I- + Acceptor + Triiodothyronine

Reduced acceptor + 3,3',5'-Triiodothyronine <-> H+ + I- + Acceptor + 3,3'-Diiodothyronine

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 1.21.99.4