Enzyme Details

 EC Classification 1.3.1.2
 Enzyme name
(recommended)
dihydropyrimidine dehydrogenase (NADP+)
 Alternative names 5,6-dihydrouracil:NADP+ 5-oxidoreductase
dihydrothymine dehydrogenase
dihydrouracil dehydrogenase (NADP+)
4,5-dihydrothymine: oxidoreductase
DPD
DHPDH
dehydrogenase, dihydrouracil (nicotinamide adenine dinucleotide phosphate)
dihydrouracil dehydrogenase (NADP+)
DHU dehydrogenase
hydropyrimidine dehydrogenase
dihydropyrimidine dehydrogenase (NADP+)
 Classification
Oxidoreductases
Acting on the CH-CH group of donors
With NAD(+) or NADP(+) as acceptor
 Catalyses reactions
NADP+ + 5,6-Dihydrouracil <-> H+ + Uracil + NADPH
NADP+ + 5,6-Dihydrothymine <-> H+ + Thymine + NADPH
 External links Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop


View all entries for EC Class: 1.3.1.2



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