Enzyme Details

EC Classification

1.3.99.12

Enzyme name
(recommended)

2-methylacyl-CoA dehydrogenase

Alternative names

2-methylbutanoyl-CoA:acceptor oxidoreductase
branched-chain acyl-CoA dehydrogenase
2-methyl branched chain acyl-CoA dehydrogenase
2-methylbutanoyl-CoA:(acceptor) oxidoreductase

Classification

Oxidoreductases

Acting on the CH-CH group of donors

With other acceptors

Catalyses reactions

FAD + 2-Methylpropanoyl-CoA <-> FADH2 + 2-Methylprop-2-enoyl-CoA

FAD + 2-Methylbutanoyl-CoA <-> FADH2 + 2-Methylbut-2-enoyl-CoA

2-Methylbutanoyl-CoA + Acceptor <-> Reduced acceptor + 2-Methylbut-2-enoyl-CoA

Electron-transferring flavoprotein + (S)-2-Methylbutanoyl-CoA <-> 2-Methylbut-2-enoyl-CoA + Reduced electron-transferring flavoprotein

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 1.3.99.12