Enzyme Details

EC Classification

1.4.1.2

Enzyme name
(recommended)

glutamate dehydrogenase

Alternative names

L-glutamate:NAD+ oxidoreductase (deaminating)
glutamic dehydrogenase
glutamate dehydrogenase (NAD+)
glutamate oxidoreductase
glutamic acid dehydrogenase
L-glutamate dehydrogenase
NAD+-dependent glutamate dehydrogenase
NAD+-dependent glutamic dehydrogenase
NAD+-glutamate dehydrogenase
NAD+-linked glutamate dehydrogenase
NAD+-linked glutamic dehydrogenase
NAD+-specific glutamic dehydrogenase
NAD+-specific glutamate dehydrogenase
NAD+:glutamate oxidoreductase
NADH-linked glutamate dehydrogenase

Classification

Oxidoreductases

Acting on the CH-NH(2) group of donors

With NAD(+) or NADP(+) as acceptor

Catalyses reactions

NAD+ + H2O + alpha-Amino acid <-> NADH + H+ + NH3 + 2-Oxo acid

H2O + NADP+ + alpha-Amino acid <-> H+ + NADPH + NH3 + 2-Oxo acid

NAD+ + H2O + L-Glutamate <-> NADH + H+ + NH3 + 2-Oxoglutarate

NAD+ + H2O + L-Methionine <-> NADH + H+ + NH3 + 4-Methylthio-2-oxobutanoate

NAD+ + H2O + L-Norleucine <-> NADH + H+ + NH3 + 2-Oxohexanoate

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 1.4.1.2