Enzyme Details

EC Classification

1.4.1.4

Enzyme name
(recommended)

glutamate dehydrogenase (NADP+)

Alternative names

L-glutamate:NADP+ oxidoreductase (deaminating)
glutamic dehydrogenase
dehydrogenase, glutamate (nicotinamide adenine dinucleotide (phosphate))
glutamic acid dehydrogenase
L-glutamate dehydrogenase
L-glutamic acid dehydrogenase
NAD(P)+-glutamate dehydrogenase
NAD(P)H-dependent glutamate dehydrogenase
glutamate dehydrogenase (NADP+)

Classification

Oxidoreductases

Acting on the CH-NH(2) group of donors

With NAD(+) or NADP(+) as acceptor

Catalyses reactions

NAD+ + H2O + alpha-Amino acid <-> NADH + H+ + NH3 + 2-Oxo acid

H2O + NADP+ + alpha-Amino acid <-> H+ + NADPH + NH3 + 2-Oxo acid

NAD+ + H2O + L-Glutamate <-> NADH + H+ + NH3 + 2-Oxoglutarate

H2O + L-Glutamate + NADP+ <-> H+ + NADPH + NH3 + 2-Oxoglutarate

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 1.4.1.4