Enzyme Details

EC Classification

1.5.1.6

Enzyme name
(recommended)

formyltetrahydrofolate dehydrogenase

Alternative names

10-formyltetrahydrofolate:NADP+ oxidoreductase
10-formyl tetrahydrofolate:NADP oxidoreductase
10-formyl-H2PtGlu:NADP oxidoreductase
10-formyl-H4folate dehydrogenase
N10-formyltetrahydrofolate dehydrogenase
10-formyltetrahydrofolate dehydrogenase

Classification

Oxidoreductases

Acting on the CH-NH group of donors

With NAD(+) or NADP(+) as acceptor

Catalyses reactions

H2O + NADP+ + 10-Formyltetrahydrofolate <-> H+ + NADPH + CO2 + 5,6,7,8-Tetrahydrofolate

H2O + NADP+ + Propanal <-> H+ + NADPH + Propanoate

H2O + NADP+ + 10-Formyl-5,8-dideazafolate <-> H+ + NADPH + CO2 + 5,8-Dideazafolate

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 1.5.1.6