Enzyme Details

EC Classification

1.5.1.8

Enzyme name
(recommended)

saccharopine dehydrogenase (NADP+, L-lysine-forming)

Alternative names

N6-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming)
lysine-2-oxoglutarate reductase
lysine-ketoglutarate reductase
L-lysine-alpha-ketoglutarate reductase
lysine:alpha-ketoglutarate:TPNH oxidoreductase (epsilon-N-[gultaryl-2]-L-lysine forming)
saccharopine (nicotinamide adenine dinucleotide phosphate, lysine-forming) dehydrogenase
6-N-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming)

Classification

Oxidoreductases

Acting on the CH-NH group of donors

With NAD(+) or NADP(+) as acceptor

Catalyses reactions

H2O + NADP+ + N6-(L-1,3-Dicarboxypropyl)-L-lysine <-> H+ + L-Lysine + NADPH + 2-Oxoglutarate

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 1.5.1.8