Enzyme Details

EC Classification

1.6.2.2

Enzyme name
(recommended)

cytochrome-b5 reductase

Alternative names

NADH:ferricytochrome-b5 oxidoreductase
cytochrome b5 reductase
dihydronicotinamide adenine dinucleotide-cytochrome b5 reductase
reduced nicotinamide adeninedinucleotide-cytochrome b5 reductase
NADH-ferricytochrome b5 oxidoreductase
NADH-cytochrome b5 reductase
NADH 5alpha-reductase
NADH-cytochrome-b5 reductase

Classification

Oxidoreductases

Acting on NADH or NADPH

With a cytochrome as acceptor

Catalyses reactions

NADH + H+ + 2 Ferricytochrome b5 <-> NAD+ + 2 Ferrocytochrome b5

NADH + 2 Hexacyanoferrate(III) <-> NAD+ + H+ + 2 Hexacyanoferrate(II)

NADPH + 2 Hexacyanoferrate(III) <-> H+ + NADP+ + 2 Hexacyanoferrate(II)

NADH + H+ + Cytochrome c <-> NAD+ + Reduced cytochrome c

H+ + NADPH + Cytochrome c <-> NADP+ + Reduced cytochrome c

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 1.6.2.2