Enzyme Details

EC Classification

1.8.1.15

Enzyme name
(recommended)

mycothione reductase

Alternative names

mycothiol:NAD(P)+ oxidoreductase
mycothiol-disulfide reductase

Classification

Oxidoreductases

Acting on a sulfur group of donors

With NAD(+) or NADP(+) as acceptor

Catalyses reactions

NAD+ + 2 Mycothiol <-> NADH + H+ + Mycothione

NADP+ + 2 Mycothiol <-> H+ + NADPH + Mycothione

H+ + NADPH + Desmyoinositol mycothione <-> NADP+ + 2 Desmyoinositol mycothiol

H+ + NHDPH + Desmyoinositol mycothione <-> NHDP+ + 2 Desmyoinositol mycothiol

NADH + H+ + Desmyoinositol mycothione <-> NAD+ + 2 Desmyoinositol mycothiol

H+ + Deamino-NADH + Desmyoinositol mycothione <-> Nicotinamide hypoxanthine dinucleotide + 2 Desmyoinositol mycothiol

H+ + thio-NADPH + Desmyoinositol mycothione <-> thio-NADP+ + 2 Desmyoinositol mycothiol

H+ + thio-NADH + Desmyoinositol mycothione <-> thio-NAD+ + 2 Desmyoinositol mycothiol

H+ + alpha-NADPH + Desmyoinositol mycothione <-> alpha-NADP+ + 2 Desmyoinositol mycothiol

H+ + NADPH + 5,5'-Dithiobis(2-nitrobenzoic acid) <-> NADP+ + 2 2-Nitro-5-thiobenzoic acid

H+ + NADPH + 2,6-Dimethyl-1,4-benzoquinone <-> NADP+ + 2,6-Dimethylhydroquinone

H+ + NADPH + 5-Hydroxy-1,4-naphthoquinone <-> NADP+ + 1,4,5-Naphthalenetriol

2 H+ + 2 NADPH + Naphthazarin <-> 2 NADP+ + 5,8-Dihydroxy-hydronaphthoquinone

H+ + NADPH + Menadione <-> NADP+ + Menadiol

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 1.8.1.15

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