Enzyme Details

EC Classification

2.3.1.87

Enzyme name
(recommended)

aralkylamine N-acetyltransferase

Alternative names

acetyl-CoA:2-arylethylamine N-acetyltransferase
serotonin acetyltransferase
serotonin acetylase
arylalkylamine N-acetyltransferase
serotonin N-acetyltransferase
AANAT
melatonin rhythm enzyme

Classification

Transferases

Acyltransferases

Catalyses reactions

Acetyl-CoA + Serotonin <-> Coenzyme A + N-Acetylserotonin

Acetyl-CoA + Arylalkylamine <-> Coenzyme A + N-Acetylarylalkylamine

Acetyl-CoA + Tryptamine <-> Coenzyme A + N-Acetyltryptamine

Acetyl-CoA + Tyramine <-> Coenzyme A + N-Acetyltyramine

Acetyl-CoA + 2-Phenylethylamine <-> Coenzyme A + N-Acetylphenylethylamine

Coenzyme A + N-Bromoacetyltryptamine <-> Hydrobromic acid + CoA-S-acetyl tryptamine

Acetyl-CoA + 5-Methoxytryptamine <-> Coenzyme A + Melatonin

Acetyl-CoA + alpha-Methyltryptamine <-> Coenzyme A + N-Acetyl-alpha-methyltryptamine

Acetyl-CoA + 6-Fluorotryptamine <-> Coenzyme A + N-Acetyl-6-Fluorotryptamine

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 2.3.1.87