Enzyme Details

EC Classification

2.5.1.15

Enzyme name
(recommended)

dihydropteroate synthase

Alternative names

(2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl-diphosphate:4-aminobenzoate 2-amino-4-hydroxydihydropteridine-6-methenyltransferase
dihydropteroate pyrophosphorylase
DHPS
7,8-dihydropteroate synthase
7,8-dihydropteroate synthetase
7,8-dihydropteroic acid synthetase
dihydropteroate synthetase
dihydropteroic synthetase
2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine-diphosphate:4-aminobenzoate 2-amino-4-hydroxydihydropteridine-6-methenyltransferase

Classification

Transferases

Transferring alkyl or aryl groups, other than methyl groups

Catalyses reactions

4-Aminobenzoate + 2-Amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine <-> H2O + Dihydropteroate

2-Amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + 4-Aminobenzoate <-> Diphosphate + Dihydropteroate

2-Amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + 4-Aminobenzoyl glutamate <-> Diphosphate + Dihydrofolate

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 2.5.1.15