Enzyme Details

EC Classification

2.5.1.18

Enzyme name
(recommended)

glutathione transferase

Alternative names

RX:glutathione R-transferase
glutathione S-transferase
glutathione S-alkyltransferase
glutathione S-aryltransferase
S-(hydroxyalkyl)glutathione lyase
glutathione S-aralkyltransferase
glutathione S-alkyl transferase
GST

Classification

Transferases

Transferring alkyl or aryl groups, other than methyl groups

Catalyses reactions

Reduced glutathione + RX <-> HX + R-S-Glutathione

Reduced glutathione + 1-Fluoro-2,4-dinitrobenzene <-> S-(2,4-Dinitrophenyl)glutathione + HF

Reduced glutathione + 1-Chloro-2,4-dinitrobenzene <-> HCl + S-(2,4-Dinitrophenyl)glutathione

Reduced glutathione + (+)-anti-BPDE <-> Glutathione conjugate of (+)-anti-BPDE

Reduced glutathione + (-)-anti-BPDE <-> Glutathione conjugate of (-)-anti-BPDE

Reduced glutathione + Bromodichlormethane <-> Hydrobromic acid + S-Dichlormethyl-glutathione

Androst-5-ene-3,17-dione <-> Androst-4-ene-3,17-dione

H2O + S-Glutathionyl benzoate <-> Benzoate + Reduced glutathione

Reduced glutathione + Monobromobimane <-> Hydrobromic acid + S-(Gluthathionyl)-bimane

Reduced glutathione + Ethacrynic acid <-> HCl + S-(Ethacrynyl)glutathione

Reduced glutathione + Benzyl isothiocyanate <-> S-(N-Benzylthiocarbamoyl)glutathione

Reduced glutathione + Sulforaphane <-> S-(N-(4-Methylsulfinyl)butylthiocarbamoyl)glutathione

Reduced glutathione + Phenethyl isothiocyanate <-> S-(N-Phenethylthiocarbamoyl)glutathione

Reduced glutathione + Ethacrynic acid <-> Ethacrynic acid glutathione conjugate

Reduced glutathione + Dichloromethane <-> HCl + S-Chloromethyl glutathione

Reduced glutathione + 4-Chloro-3,5-dinitrobenzoic acid <-> HCl + S-(3,5-Dinitrobenzoyl)glutathione

Reduced glutathione + Dibromomethane <-> Hydrobromic acid + S-Bromomethyl glutathione

Reduced glutathione + 7-Chloro-4-nitrobenzo-2-oxa-1,3-diazole <-> HCl + S-(4-Nitrophenyl-2-oxa-1,3-diazole)glutathione

Reduced glutathione + 4-Nitrocinnamaldehyde <-> 4-Nitrocinnamaldehyde glutathione conjugate

Reduced glutathione + 4-Vinylpyridine <-> S-(4-Ethylpyridine)glutathione

Reduced glutathione + Phosphonomycin <-> 2-Hydroxy-3-(S-glutathionyl)propylphosphonate

Reduced glutathione + Ketoprofenyl-acyl-CoA <-> Coenzyme A + Ketoprofenyl-S-acyl-glutathione

Reduced glutathione + 1,2-Dichloro-4-nitrobenzene <-> HCl + S-(2-Chloro-4-nitrophenyl)glutathione

2 Reduced glutathione + (beta-(13-Hydroperoxy-cis-9, trans-11-octadecadienoyl)-gamma-palmitoyl)-L-alpha-phosphatidylcholine <-> Unknown + 2 H2O + Oxidized glutathione

S-Methyl GSH + 1-Chloro-2,4-dinitrobenzene <-> Unknown + HCl

Reduced glutathione + 1-Bromo-2,4-dinitrobenzene <-> S-(2,4-Dinitrophenyl)glutathione + Hydrobromic acid

Reduced glutathione + 1-Iodo-2,4-dinitrobenzene <-> HI + S-(2,4-Dinitrophenyl)glutathione

2 Reduced glutathione + Cumene hydroperoxide <-> H2O + Oxidized glutathione + 2-Phenyl-2-propanol

Reduced glutathione + Allyl isothiocyanate <-> S-(N-Allylthiocarbamoyl)glutathione

2 Reduced glutathione + Hydroxyethyl disulfide <-> Oxidized glutathione + 2 2-Mercaptoethanol

Reduced glutathione + Bromoacetate <-> Br- + 2-S-Glutathionyl acetate

Reduced glutathione + 4-Hydroxy-2-nonenal <-> 4-Hydroxynonenal glutathione conjugate

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 2.5.1.18