Enzyme Details

EC Classification

2.5.1.21

Enzyme name
(recommended)

squalene synthase

Alternative names

farnesyl-diphosphate:farnesyl-diphosphate farnesyltransferase
farnesyltransferase
presqualene-diphosphate synthase
presqualene synthase
squalene synthetase
farnesyl-diphosphate farnesyltransferase
SQS

Classification

Transferases

Transferring alkyl or aryl groups, other than methyl groups

Catalyses reactions

2 trans,trans-Farnesyl diphosphate <-> H+ + Diphosphate + Presqualene diphosphate

H+ + NADPH + Presqualene diphosphate <-> NADP+ + Diphosphate + Squalene

H+ + NADPH + 2 trans,trans-Farnesyl diphosphate <-> NADP+ + 2 Diphosphate + Squalene

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 2.5.1.21