Enzyme Details
EC Classification
2.5.1.48
Enzyme name
(recommended)
cystathionine gamma-synthase
Alternative names
cystathionine synthetase
O4-succinyl-L-homoserine:L-cysteine S-(3-amino-3-carboxypropyl)transferase
O-succinyl-L-homoserine succinate-lyase (adding cysteine)
O-succinylhomoserine (thiol)-lyase
homoserine O-transsuccinylase
O-succinylhomoserine synthase
O-succinylhomoserine synthetase
cystathionine synthase
homoserine transsuccinylase
4-O-succinyl-L-homoserine:L-cysteine S-(3-amino-3-carboxypropyl)transferase
Classification
Transferases
Transferring alkyl or aryl groups, other than methyl groups
Transferring alkyl or aryl groups, other than methyl groups
Catalyses reactions
H2O + O-Succinyl-L-homoserine <-> NH3 + Succinate + 2-Oxobutyrate
O-Succinyl-L-homoserine + Sulfide <-> Succinate + L-Homocysteine
Succinate + Cystathionine <-> L-Cysteine + O-Succinyl-L-homoserine
O-Acetyl-L-serine + Thiosulfate <-> Acetate + S-Sulfo-L-cysteine
L-Cysteine + O-Succinyl-L-homoserine <-> Succinate + L-Cystathionine
Selenocysteine + O-Phosphorylhomoserine <-> Phosphate + Selenocystathionine
Selenocysteine + O-Acetylhomoserine <-> Acetate + Selenocystathionine
Selenocysteine + O-Succinylhomoserine <-> Succinate + Selenocystathionine
L-Cysteine + 2 O-Succinyl-L-homoserine <-> Pyruvate + NH3 + 2 Succinate + L-Cystathionine
O-Succinyl-L-homoserine <-> Pyruvate + NH3 + Succinate
L-Cysteine + O-Phospho-L-homoserine <-> Phosphate + L-Cystathionine
O-Phospho-L-homoserine + Sulfide <-> Phosphate + L-Homocysteine
H2O + O-Phospho-L-homoserine <-> Phosphate + NH3 + 2-Oxobutyrate
O-Phospho-L-homoserine + L-Cysteine methylester <-> Phosphate + S-(L-2-Amino-2-methoxycarbonyl)-L-homocysteine
2-Mercaptoethanol + O-Phospho-L-homoserine <-> Phosphate + S-Ethyl-L-homocysteine
O-Phospho-L-homoserine + Sodium sulfide <-> L-Homocysteine + Sodium phosphate
External links
Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop
View all entries for EC Class:
2.5.1.48
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