Enzyme Details

EC Classification

2.7.6.1

Enzyme name
(recommended)

ribose-phosphate diphosphokinase

Alternative names

ATP:D-ribose-5-phosphate diphosphotransferase
ribose-phosphate pyrophosphokinase
PRPP synthetase
phosphoribosylpyrophosphate synthetase
PPRibP synthetase
PP-ribose P synthetase
5-phosphoribosyl-1-pyrophosphate synthetase
5-phosphoribose pyrophosphorylase
5-phosphoribosyl-alpha-1-pyrophosphate synthetase
phosphoribosyl-diphosphate synthetase
phosphoribosylpyrophosphate synthase
pyrophosphoribosylphosphate synthetase
ribophosphate pyrophosphokinase
ribose-5-phosphate pyrophosphokinase

Classification

Transferases

Transferring phosphorous-containing groups

Diphosphotransferases

Catalyses reactions

ATP + D-Ribose 5-phosphate <-> AMP + 5-Phospho-alpha-D-ribose 1-diphosphate

D-Ribose 5-phosphate + dATP <-> dAMP + 5-Phospho-alpha-D-ribose 1-diphosphate

GTP + D-Ribose 5-phosphate <-> 5-Phospho-alpha-D-ribose 1-diphosphate + GMP

CTP + D-Ribose 5-phosphate <-> CMP + 5-Phospho-alpha-D-ribose 1-diphosphate

UTP + D-Ribose 5-phosphate <-> UMP + 5-Phospho-alpha-D-ribose 1-diphosphate

D-Ribose 5-phosphate + PrsA <-> Enzyme-ligand complex

ATP + PrsA <-> Enzyme-ligand complex

AMP-PNP + PrsA <-> Enzyme-ligand complex

ADP + PrsA <-> Enzyme-ligand complex

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 2.7.6.1