Enzyme Details

 EC Classification 3.1.4.1
 Enzyme name
(recommended)		 phosphodiesterase I
 Alternative names 5'-PDE
5'NPDE
oligonucleotide 5'-nucleotidohydrolase
5'-exonuclease
5'-phosphodiesterase
5'-nucleotide phosphodiesterase
oligonucleate 5'-nucleotidohydrolase
5' nucleotide phosphodiesterase/alkaline phosphodiesterase I
5'-NPDase
5'-PDase
alkaline phosphodiesterase
nucleotide pyrophosphatase/phosphodiesterase I
orthophosphoric diester phosphohydrolase
PDE I
phosphodiesterase (ambiguous)
exonuclease I
 Classification
Hydrolases
Acting on ester bonds
Phosphoric diester hydrolases
 Catalyses reactions
ATP + H2O <-> Diphosphate + AMP
H2O + Bis-4-nitrophenyl phosphate <-> 4-Nitrophenyl phosphate + p-Nitrophenol
H2O + p-Nitrophenylthymidine phosphate <-> dTMP + p-Nitrophenol
H2O + 4-Nitrophenyl phosphocholine <-> 4-Nitrophenyl phosphate + Choline
H2O + 4-Nitrophenyl phenyl phosphonate <-> p-Nitrophenol + Phenyl phosphonate
H2O + 4-Nitrophenyl phenyl phosphonate <-> p-Nitrophenol + Methyl phosphonate
H2O + 2-Naphthyl methylphosphonate <-> beta-Naphthol + Methyl phosphonate
H2O + 2-Naphthyl phenyl phosphonate <-> beta-Naphthol + Phenyl phosphonate
H2O + 4-Nitrophenyl chloromethylphosphonate <-> p-Nitrophenol + Chloromethylphosphonate
H2O + 2-Naphthyl chloromethylphosphonate <-> beta-Naphthol + Chloromethylphosphonate
H2O + Adenylyl-3',5'-guanosine <-> GMP + Adenosine
H2O + Adenylyl-3',5'-adenosine <-> AMP + Adenosine
H2O + Adenylyl-3',5'-cytidine <-> CMP + Adenosine
H2O + Cytidylyl-3',5'-uracil <-> UMP + Cytidine
6 H2O + U(pU)6 <-> 6 UMP + Uridine
H2O + p-Nitrophenyl uridine 5'-phosphate <-> UMP + p-Nitrophenol
 External links Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop


View all entries for EC Class: 3.1.4.1



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