Enzyme Details

 EC Classification 3.1.4.12
 Enzyme name
(recommended)
sphingomyelin phosphodiesterase
 Alternative names sphingomyelin cholinephosphohydrolase
neutral sphingomyelinase
 Classification
Hydrolases
Acting on ester bonds
Phosphoric diester hydrolases
 Catalyses reactions
H2O + Sphingomyelin <-> Choline phosphate + N-Acylsphingosine
H2O + 1-O-Hexadecyl-lyso-sn-glycero-3-phosphocholine <-> Choline phosphate + 1-O-Hexadecyl-sn-glycerol
H2O + Arachidoyllysophosphatidylcholine <-> Choline phosphate + Monoarachidin
H2O + Myristoyllysophosphatidylcholine <-> Choline phosphate + Monomyristin
H2O + Palmitoyllysophosphatidylcholine <-> Choline phosphate + Monopalmitin
H2O + Stearoyllysophosphatidylcholine <-> Choline phosphate + Monostearin
 External links Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop


View all entries for EC Class: 3.1.4.12



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