Enzyme Details

EC Classification

3.1.4.3

Enzyme name
(recommended)

phospholipase C

Alternative names

phosphatidylcholine cholinephosphohydrolase
lipophosphodiesterase I
lecithinase C
Clostridium welchii alpha-toxin
Clostridium oedematiens beta- and gamma-toxins
lipophosphodiesterase C
phosphatidase C
heat-labile hemolysin
alpha-toxin

Classification

Hydrolases

Acting on ester bonds

Phosphoric diester hydrolases

Catalyses reactions

H2O + Phosphatidylcholine <-> Choline phosphate + 1,2-Diacyl-sn-glycerol

H2O + Phosphatidylglycerol <-> sn-Glycerol 3-phosphate + 1,2-Diacyl-sn-glycerol

H2O + Phosphatidylethanolamine <-> Ethanolamine phosphate + 1,2-Diacyl-sn-glycerol

H2O + 1-Phosphatidyl-D-myo-inositol <-> 1,2-Diacyl-sn-glycerol + 1D-myo-Inositol 1-phosphate

H2O + Phosphatidylserine <-> 1,2-Diacyl-sn-glycerol + O-Phospho-L-serine

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 3.1.4.3