Enzyme Details

 EC Classification 3.3.2.6
 Enzyme name
(recommended)		 leukotriene-A4 hydrolase
 Alternative names (7E,9E,11Z,14Z)-(5S,6S)-5,6-epoxyicosa-7,9,11,14-tetraenoate hydrolase
LTA4 hydrolase
LTA4H
leukotriene A4 hydrolase
 Classification
Hydrolases
Acting on ether bonds
Ether hydrolases
 Catalyses reactions
H2O + Leukotriene A4 <-> Leukotriene B4
H2O + Leukotriene A4 <-> 5S,6S-Dihydroxy-7,9-trans-11,14-cis-eicosatetraenoic acid
H2O + L-Leucinyl-p-nitroanilide <-> L-Leucine + 4-Nitroaniline
H2O + L-Methionine-p-nitroanilide <-> L-Methionine + 4-Nitroaniline
H2O + L-Alanyl-p-nitroanilide <-> L-Alanine + 4-Nitroaniline
H2O + L-Arginyl-p-nitroanilide <-> L-Arginine + 4-Nitroaniline
H2O + Prolyl-p-nitroanilide <-> 4-Nitroaniline + Proline
H2O + L-Lysyl-p-nitroanilide <-> L-Lysine + 4-Nitroaniline
H2O + Ala-p-nitroanilide <-> Alanine + 4-Nitroaniline
 External links Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop


View all entries for EC Class: 3.3.2.6



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