Enzyme Details

EC Classification

3.4.11

Enzyme name
(recommended)

Aminopeptidases

Classification

Hydrolases

Acting on peptide bonds (peptide hydrolases)

Aminopeptidases

Catalyses reactions

H2O + alpha-Aminoisobutyryl-Gly-Gly <-> 2-Amino-2-methylpropanoate + Gly-Gly

H2O + Gly-Ala-Ala <-> Glycine + Ala-Ala

H2O + Gly-Gly-Gly <-> Glycine + Gly-Gly

H2O + Tyr-Gly-Gly <-> Tyrosine + Gly-Gly

H2O + Leu-Gly-Gly <-> Leucine + Gly-Gly

H2O + Ala-Ala-Gly <-> L-Alanine + L-Alanylglycine

H2O + Gly-Ala-Tyr <-> Glycine + Ala-Tyr

H2O + Gly-Gly-Ala <-> Glycine + Gly-Ala

H2O + Gly-Gly-Phe <-> Glycine + Gly-Phe

H2O + Ala-Ala-Ala <-> Alanine + Ala-Ala

H2O + Ala-Gly-Ala <-> Alanine + Gly-Ala

H2O + Phe-Gly-Gly <-> Phenylalanine + Gly-Gly

H2O + Ala-Gly-Gly <-> Alanine + Gly-Gly

H2O + Gly-Ala-Gly <-> Glycine + L-Alanylglycine

H2O + Ser-Gly-Gly <-> Serine + Gly-Gly

H2O + Leu-4-methylcoumaryl-7-amide <-> L-Leucine + 7-Amino-4-methylcoumarin

H2O + Met-4-methylcoumaryl-7-amide <-> L-Methionine + 7-Amino-4-methylcoumarin

H2O + Lys-4-methylcoumaryl-7-amide <-> L-Lysine + 7-Amino-4-methylcoumarin

H2O + L-Cysteinylglycine <-> Glycine + L-Cysteine

H2O + L-Leucinyl-p-nitroanilide <-> L-Leucine + 4-Nitroaniline

H2O + L-Leucyl-beta-naphthylamide <-> L-Leucine + 2-Naphthylamine

H2O + N-Succinyl-Ala-Ala-Ala-Pro-Phe-p-nitroanilide <-> 4-Nitroaniline + N-Succinyl-Ala-Ala-Ala-Pro-Phe

H2O + L-Pyroglutamyl-Pro-Arg-p-nitroanilide <-> 4-Nitroaniline + L-Pyroglutamyl-Pro-Arg

H2O + N-Succinyl-Ala-Ala-Ala-p-nitroanilide <-> 4-Nitroaniline + N-Succinyl-Ala-Ala-Ala

H2O + Phe-Arg-methylcoumarine amide <-> Phe-Arg + 7-Amino-4-methylcoumarin

H2O + Succinyl-Leu-Leu-Val-Tyr-methylcoumarine amide <-> Succinyl-Leu-Leu-Val-Tyr + 7-Amino-4-methylcoumarin

H2O + Leu-p-nitroanilide <-> 4-Nitroaniline + Leucine

H2O + Lys-p-nitroanilide <-> 4-Nitroaniline + Lysine

H2O + Ala-p-nitroanilide <-> Alanine + 4-Nitroaniline

H2O + Glu-p-nitroanilide <-> Glutamate + 4-Nitroaniline

H2O + Val-p-nitroanilide <-> 4-Nitroaniline + Valine

H2O + Prolyl-p-nitroanilide <-> 4-Nitroaniline + Proline

H2O + Ile-p-nitroanilide <-> 4-Nitroaniline + Isoleucine

H2O + 7-Methoxycoumarin-4-acetyl-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys(DNP)-D-Arg-amide <-> 7-Methoxycoumarin-4-acetic acid + Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys(DNP)-D-Arg-amide

H2O + Arg-4-methylcoumaryl-7-amide <-> L-Arginine + 7-Amino-4-methylcoumarin

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

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