Enzyme Details

EC Classification

3.4.19.3

Enzyme name
(recommended)

pyroglutamyl-peptidase I

Alternative names

pyroglutamidase
5-oxoprolyl-peptidase
pyrase
pyroglutamate aminopeptidase
pyroglutamyl aminopeptidase
L-pyroglutamyl peptide hydrolase
pyrrolidone-carboxyl peptidase
pyrrolidone-carboxylate peptidase
pyrrolidonyl peptidase
L-pyrrolidonecarboxylate peptidase
pyrrolidonecarboxylyl peptidase

Classification

Hydrolases

Acting on peptide bonds (peptide hydrolases)

Omega peptidases

Catalyses reactions

H2O + L-Pyroglutamyl-beta-naphthylamide <-> 5-Oxo-L-proline + 2-Naphthylamine

H2O + L-Pyroglutamyl-p-nitroanilide <-> 5-Oxo-L-proline + 4-Nitroaniline

H2O + L-gamma-Glutamyl-p-nitroanilide <-> L-Glutamate + 4-Nitroaniline

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 3.4.19.3