Enzyme Details

EC Classification

3.4.21.6

Enzyme name
(recommended)

coagulation factor Xa

Alternative names

thrombokinase
prothrombase
prothrombinase
thromboplastin
activated blood-coagulation factor X
autoprothrombin C
plasma thromboplastin
factor Xa
activated Stuart-Prower factor
activated factor X

Classification

Hydrolases

Acting on peptide bonds (peptide hydrolases)

Serine endopeptidases

Catalyses reactions

H2O + Factor VIII <-> Factor VIIIa

H2O + N-alpha-Cbo-D-Arg-Gly-Arg-p-nitroanilide <-> 4-Nitroaniline + N-alpha-Cbo-D-Arg-Gly-Arg

H2O + t-Butyloxycarbonyl-Ile-Glu-Gly-Arg-4-methylcoumarin-7-ylamide <-> t-Butyloxycarbonyl-Ile-Glu-Gly-Arg + 7-Amino-4-methylcoumarin

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 3.4.21.6