Enzyme Details

EC Classification

3.6.1.55

Enzyme name
(recommended)

8-oxo-dGTP diphosphatase

Alternative names

7,8-dihydro-8-oxoguanine triphosphatase
8-oxo-dGTPase
7,8-dihydro-8-oxo-dGTP pyrophosphohydrolase

Classification

Hydrolases

Acting on acid anhydrides

In phosphorous-containing anhydrides

Catalyses reactions

H2O + Coenzyme A <-> Adenosine 3',5'-bisphosphate + 4'-Phosphopantetheine

H2O + CoA-disulfide <-> Adenosine 3',5'-bisphosphate + CoA-4'-Phosphopantetheine disulfide

H2O + 8-oxo-dGTP <-> Diphosphate + 8-oxo-dGMP

H2O + dGTP <-> dGMP + Diphosphate

H2O + dATP <-> dAMP + Diphosphate

H2O + dTTP <-> dTMP + Diphosphate

H2O + 8-oxo-GTP <-> Diphosphate + 8-oxo-GMP

NADH + H2O <-> AMP + Reduced nicotinamide nucleotide

H2O + P1,P4-Bis(5'-adenosyl) tetraphosphate <-> ATP + AMP

H2O + Bis(5'-adenosyl) pentaphosphate <-> ATP + ADP

H2O + 8-oxo-dGDP <-> Phosphate + 8-oxo-dGMP

H2O + 8-oxo-GDP <-> Phosphate + 8-oxo-GMP

H2O + GTP <-> Diphosphate + GMP

H2O + GDP <-> Phosphate + GMP

H2O + dGDP <-> Phosphate + dGMP

H2O + dADP <-> Phosphate + dAMP

H2O + dCDP <-> Phosphate + dCMP

H2O + dTDP <-> Phosphate + dTMP

H2O + dCTP <-> dCMP + Diphosphate

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 3.6.1.55

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